Search Results - tissue engineering

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Multi-Needle Roller for Cell Seeding
Seeding cells within scaffolds or tissues hold great potential for regenerative medicine projects. Until now, cells have been either placed on top of scaffolds, creating multiple layers of superficial cells, or injected manually with a syringe inside the tissues, generating large boluses of cells. None of these approaches generated the homogenous, ...
Published: 1/7/2019   |   Inventor(s): Dan Simionescu, Benjamin Fisher, Harrison Smallwood
Keywords(s): Bioprocessing/Biotechnology, Medical Device, Regenerative Medicine, Tissue Engineering
Category(s): Biomedical Sciences
Biphasic Osteochondral Construct for Cartilage Tissue Repair (09-026)
This osteochondral construct is seeded with mesenchymal stem cells to encourage repair of cartilage and subchondral bone in synovial joints. The global market for tissue engineering and regeneration is expected to grow from $13.6 billion in 2016 to $60.8 billion in 2021, in part due to the 5.4 million patients projected to require joint and cartila...
Published: 3/9/2017   |   Inventor(s): Karen Burg, Scott Maxson
Keywords(s): Biomaterials - Orthopaedic, Medical Device, Orthopaedics-Biologics/Tissue Engr/Regen Medicine, Tissue Engineering
Category(s): Biomedical Sciences
Injectable Joint Lubricant for Treating Osteoarthritis (00-001)
This dextran-based hydrogel uses phospholipid delivery to treat degenerative joint diseases, also known as osteoarthritis. Osteoarthritis is the most common type of arthritis, affecting over 27 million Americans over the age of 25. It becomes more common with age, often affecting the neck, lower back, knees, and hips. Normally synovial fluid, a nat...
Published: 9/8/2016   |   Inventor(s): Julie-Ann Burdick, Martine Laberge, Gary Lickfield
Keywords(s): Biomaterials - Other, Drugs/Pharma - Drug Delivery, Medical Device, Tissue Engineering
Category(s): Biomedical Sciences
Topical Application of Hydrogel for the Treatment of Acute Spinal Cord Injury (2011-072)
This hydrogel can be used for the non-invasive treatment of acute spinal cord injuries by applying topically to the injury site. According to the Centers for Disease Control and Prevention, about 450,000 people in the United States are currently living with a spinal cord injury and 12,000 new cases develop each year. The cost of rehabilitation and ...
Published: 7/12/2016   |   Inventor(s): Xing Jin, Vibhor Krishna, Xuejun Wen, Ning Zhang
Keywords(s): Biomaterials - Neurology, Drugs/Pharma - Drug Delivery, Molecular Therapies, Regenerative Medicine, Tissue Engineering
Category(s): Biomedical Sciences
Elastogenic Effects of Hyaluronan Oligosaccharides and Their Applications in Tissue Engineering (includes 07-054)
Elastin is a critical component in all connective tissue and is not readily regenerated by the body. In order to develop or regenerate functional connective tissue, elastogenic cues to synthesize, organize, and stabilize the extracellular matrix are critical.The invention includes novel elastogenic cues for injured or developing connective tissues ...
Published: 12/15/2009   |   Inventor(s): Anand Ramamurthi, Chandrasekhar Kothapalli, Binata Joddar
Keywords(s): Biomaterials - Cardiovascular, Medical Device, Tissue Engineering
Category(s): Biomedical Sciences
Deposition of Nanocrystalline Calcite on Metal Alloys by a Cellular Biomineralization Means and process for Preparing Same
These technologies feature a method for deposition of nano-crystalline calcite plates by specialized epithelial tissue or cells onto metallic surfaces, such as stainless steel or other alloys. This is the first demonstration of a novel crystalline material that is produced by animal tissues which can be produced in a highly controlled process. This...
Published: 12/15/2009   |   Inventor(s): Andrew Mount, Neeraj Gohad, Douglas Hansen, Karolyn Hansen, Marybeth Johnstone
Keywords(s): Molecular Therapies, Nanotechnology, Tissue Engineering
Category(s): Biomedical Sciences
Specialized Wicking Fiber Bundles for 3-D Tissue Engineering Systems
This invention is an enhancement to an engineered tissue system that may be used in drug discovery, vaccine development, biomaterial development or developmental cell biology. The enhancement allows biologically relevant tissues to be grown ex vivo. This invention uses lobed/channeled fibers, where lobed/channeled indicates a non-circular cross-sec...
Published: 12/14/2009   |   Inventor(s): Karen Burg, Chih-Chao Yang
Keywords(s): Biomaterials - Other, Medical Device, Textiles/Fibers - Non-Optical/Medical/Other, Tissue Engineering
Category(s): Biomedical Sciences
Injectable Hydrogel System for the Treatment of Stroke and Nervous Tissue Injury
Over 1.7 million Americans in the US sustain traumatic brain injury (TBI) each year[1] and an estimated 3.2 million Americans have long term disabling effects from TBI[2]. This novel and effective technology features an injectable biomaterial gel with the ability to promote functional tissue regeneration at the site of a traumatic brain injury and...
Published: 12/10/2009   |   Inventor(s): Xuejun Wen, Ning Zhang
Keywords(s): Biomaterials - Neurology, Medical Device, Regenerative Medicine, Tissue Engineering
Category(s): Biomedical Sciences
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