Search Results - biomaterials - cardiovascular

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Improved Fixation Method for Bioprosthetic Heart Valves
Bioprosthetic Heart Valves can replace defective or diseased heart valves, but a majority of these valves fail within a few years due to calcification and degeneration. Currently used methods of fixation, such as glutaraldehyde crosslinking, are not adequate to fix all extracellular matrix components, especially glycosaminoglycans (GAGs) present in...
Published: 4/28/2020   |   Inventor(s): Narendra Vyavahare, Devanathan Raghavan
Keywords(s): Biomaterials - Cardiovascular, Medical Device
Category(s): Biomedical Sciences
New Material for Transcatheter Bioprosthetic Heart Valves
This technology features a biomaterial useful for bioprostheses, such as bioprosthetic heart valves (BHVs), in which the fixed tissue has improved elastic properties. The high elastin-containing biomaterial is further characterized by having anisotropic properties wherein the biological material has a greater stiffness in one direction and a greater...
Published: 12/31/2018   |   Inventor(s): Narendra Vyavahare, Dan Simionescu
Keywords(s): Biomaterials - Cardiovascular, Medical Device
Category(s): Biomedical Sciences
Elastogenic Effects of Hyaluronan Oligosaccharides and Their Applications in Tissue Engineering (includes 07-054)
Elastin is a critical component in all connective tissue and is not readily regenerated by the body. In order to develop or regenerate functional connective tissue, elastogenic cues to synthesize, organize, and stabilize the extracellular matrix are critical.The invention includes novel elastogenic cues for injured or developing connective tissues (i.e....
Published: 12/15/2009   |   Inventor(s): Anand Ramamurthi, Chandrasekhar Kothapalli, Binata Joddar
Keywords(s): Biomaterials - Cardiovascular, Medical Device, Tissue Engineering
Category(s): Biomedical Sciences
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