Search Results - medical device

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Improved Fixation Method for Bioprosthetic Heart Valves
Bioprosthetic heart valves (BHVs) are used clinically to replace defective or diseased heart valves, but a majority of these valves fail within a few years due to calcification and degeneration. Currently used methods of fixation, such as glutaraldehyde crosslinking, are not adequate to fix all extracellular matrix components, especially glycosamin...
Published: 5/2/2019   |   Inventor(s): Narendra Vyavahare, Devanathan Raghavan
Keywords(s): Biomaterials - Cardiovascular, Medical Device
Category(s): Biomedical Sciences
Multi-Needle Roller for Cell Seeding
Seeding cells within scaffolds or tissues hold great potential for regenerative medicine projects. Until now, cells have been either placed on top of scaffolds, creating multiple layers of superficial cells, or injected manually with a syringe inside the tissues, generating large boluses of cells. None of these approaches generated the homogenous, ...
Published: 1/7/2019   |   Inventor(s): Dan Simionescu, Benjamin Fisher, Harrison Smallwood
Keywords(s): Bioprocessing/Biotechnology, Medical Device, Regenerative Medicine, Tissue Engineering
Category(s): Biomedical Sciences
New Material for Transcatheter Bioprosthetic Heart Valves
This technology features a biomaterial useful for bioprostheses, such as bioprosthetic heart valves (BHVs), in which the fixed tissue has improved elastic properties. The high elastin-containing biomaterial is further characterized by having anisotropic properties wherein the biological material has a greater stiffness in one direction and a greate...
Published: 12/31/2018   |   Inventor(s): Narendra Vyavahare, Dan Simionescu
Keywords(s): Biomaterials - Cardiovascular, Medical Device
Category(s): Biomedical Sciences
Smart Orthopedic Screws for Imaging through Tissue (2012-018)
These smart orthopedic screws allow physicians to noninvasively detect and monitor the health of bone implants, potentially preventing infection and implant loosening over time. In the United States, musculoskeletal injuries affect over 28 million patients annually – at least two million of which require fracture fixation surgery. These surge...
Published: 8/21/2018   |   Inventor(s): Jeffrey Anker, Jonathan Heath, Dakota Anderson, Melissa Rogalski
Keywords(s): Bioinstrumentation, Biomaterials - Orthopaedic, Medical Device, Orthopaedics - Orthotics/Prosthetics/Hardware/Other
Category(s): Biomedical Sciences
Durable Polymeric Antimicrobial Coating for Orthopedics (2017-059)
External fixation is a well-established orthopedic practice in which fractured bones or fusion sites are immobilized for healing by placing wires and/or pins into the bone on either side. Unfortunately, both superficial and deep tissue infections are prevalent with the use of external fixators, particularly Staphylococcal infections. The economic b...
Published: 2/8/2018   |   Inventor(s): Alexey Vertegel, Igor Luzinov, Christopher Gross, Dmitry Gil, Nikolay Borodinov
Keywords(s): Biomaterials - Orthopaedic, Coatings, Medical Device, Orthopaedics - Orthotics/Prosthetics/Hardware/Other
Category(s): Biomedical Sciences
Biphasic Osteochondral Construct for Cartilage Tissue Repair (09-026)
This osteochondral construct is seeded with mesenchymal stem cells to encourage repair of cartilage and subchondral bone in synovial joints. The global market for tissue engineering and regeneration is expected to grow from $13.6 billion in 2016 to $60.8 billion in 2021, in part due to the 5.4 million patients projected to require joint and cartila...
Published: 3/9/2017   |   Inventor(s): Karen Burg, Scott Maxson
Keywords(s): Biomaterials - Orthopaedic, Medical Device, Orthopaedics-Biologics/Tissue Engr/Regen Medicine, Tissue Engineering
Category(s): Biomedical Sciences
Inherently Omniphobic Fibers and Fabrics (2016-025)
This fiber modification uses channels with re-entrant features in the shape of repeating trapezoids to create highly repellent textiles that resist attraction of both water and liquid chemicals, solvents, and oils. The self-cleaning textiles market, which includes hydrophobic, oleophobic, and omniphobic materials, is expected to reach a value of $5...
Published: 2/1/2017   |   Inventor(s): Philip Brown, Quoc Truong, Nicole Hoffman
Keywords(s): Medical Device, Textiles/Fibers - Non-Optical/Medical/Other
Category(s): Advanced Materials, Biotechnology
Electromagnetic Catheter Tracking System to Reduce Radiation Exposure (2011-122)
This electromagnetic catheter tracking system improves surgical intervention while reducing radiation exposure to pediatric cardiology patients. As congenital heart disease (CHD) cases continue to rise in children, the pediatric interventional cardiology market is expected rise as well, reaching a value of $1,379.1 million by 2018. While many thera...
Published: 1/20/2017   |   Inventor(s): David Kwartowitz, Hamilton Baker, Fuad Mefleh
Keywords(s): Bioinstrumentation, Cardiovascular, Image-Guided Surgery, Medical Device, Medical Imaging
Category(s): Biomedical Sciences
Portable Device for Diagnosis and Monitoring of Rotator Cuff Disease (2012-106)
This device utilizes ultrasound imaging to diagnose and monitor rotator cuff injuries. Each year there are over three million new cases of rotator cuff disease. Among those affected, more than half the population over 60 suffer from rotator cuff disease. Shoulder injuries, and particularly rotator cuff disease, can be difficult to diagnose. To give...
Published: 1/20/2017   |   Inventor(s): David Kwartowitz, Erika Trent, Fuad Mefleh, Vipul Raikar, Delphine Dean
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioinstrumentation, Medical Device, Orthopaedics - Orthotics/Prosthetics/Hardware/Other
Category(s): Biomedical Sciences
Higher Luminosity Organic Fluorophores for More Efficient Plastic Scintillators (2016-019)
These organic fluorophores have enhanced luminosity in response to ionizing radiation, increasing the efficiency of plastic scintillators and providing greater environmental stability. With increasing investments in radiation monitoring for homeland security, the scintillator market is expected to reach $479.16 Million by 2020. Currently available ...
Published: 9/21/2016   |   Inventor(s): Valery Bliznyuk, Ayman Seliman, Timothy Devol, Nadezhda Derevyanko, Alexander Ishchenko
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Medical Device, Optical Fibers/Materials/Other
Category(s): Advanced Materials
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