Search Results - tissue engineering

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Biphasic Osteochondral Construct for Cartilage Tissue Repair (09-026)
This osteochondral construct is seeded with mesenchymal stem cells to encourage repair of cartilage and subchondral bone in synovial joints. The global market for tissue engineering and regeneration is expected to grow from $13.6 billion in 2016 to $60.8 billion in 2021, in part due to the 5.4 million patients projected to require joint and cartila...
Published: 3/9/2017   |   Inventor(s): Karen Burg, Scott Maxson
Keywords(s): Biomaterials, Biomaterials Implant Design, Fibers & Films, Medical Device, Orthopaedic Mechanics, Tissue Engineering
Category(s): Biomedical Sciences
New Promoter for Driving Tissue-Specific Gene Expression in Plants (2014-074)
This promoter drives constitutive and/or tissue-specific expression of genes in transgenic plants. A promoter is a specific DNA sequence that regulates the expression of downstream coding or other noncoding nucleic acids. As such, promoters are important molecular tools for agricultural biotechnology. There are two main constitutive promoters curre...
Published: 1/17/2017   |   Inventor(s): Hong Luo, Ning Yuan
Keywords(s):  
Category(s): Biotechnology
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases (2016-060)
This bi-functional RGD peptide helps identify ligands and improve functions of endothelial cells, allowing for the development of biomaterials to treat ischemic diseases. According to the Center for Disease Control and Prevention, over 795,000 people in the United States suffer a stroke each year. Of these cases, 87 percent are caused by ischemia &...
Published: 10/11/2016   |   Inventor(s): Ying Mei, Jia Jia, Chung-Jen Chou
Keywords(s): Biomaterials, Biomedical Engineering, Medical Device
Category(s): Biomedical Sciences
Injectable Joint Lubricant for Treating Osteoarthritis (00-001)
This dextran-based hydrogel uses phospholipid delivery to treat degenerative joint diseases, also known as osteoarthritis. Osteoarthritis is the most common type of arthritis, affecting over 27 million Americans over the age of 25. It becomes more common with age, often affecting the neck, lower back, knees, and hips. Normally synovial fluid, a nat...
Published: 9/8/2016   |   Inventor(s): Julie-Ann Burdick, Martine Laberge, Gary Lickfield
Keywords(s): Biomaterials, Medical Device, Molecular Therapies, Orthopaedic Mechanics, Tissue Engineering
Category(s): Biomedical Sciences
Topical Application of Hydrogel for the Treatment of Acute Spinal Cord Injury (2011-072)
This hydrogel can be used for the non-invasive treatment of acute spinal cord injuries by applying topically to the injury site. According to the Centers for Disease Control and Prevention, about 450,000 people in the United States are currently living with a spinal cord injury and 12,000 new cases develop each year. The cost of rehabilitation and ...
Published: 7/12/2016   |   Inventor(s): Xing Jin, Vibhor Krishna, Xuejun Wen, Ning Zhang
Keywords(s): Biomaterials, Drugs / Pharma, Molecular Therapies, Regenerative Medicine, Tissue Engineering, Treatment Method
Category(s): Biomedical Sciences
Shape-Memory Sponge Hydrogel for Tissue Engineering Applications (2011-088)
This hydrogel composite is composed of elastin, glycosaminoglycan and collagen (EGC) that exhibits unique shape-memory sponge characteristics. This EGC hydrogel has broad applications in tissue engineering and biomaterials, specifically regarding its use as a nucleus pulposus (NP) replacement material. Spinal disc degeneration begins within the NP ...
Published: 5/18/2016   |   Inventor(s): Dan Simionescu, Jeremy Mercuri
Keywords(s): Biomaterials, Medical Device, Regenerative Medicine, Stem-Cell Engineering, Tissue Engineering
Category(s): Biomedical Sciences
Protein Jet Printing onto Solid Substrata
Ink-Jet Printing of Viable Cells This patented technology describes the utilization of ink-jet printing of living cells (eukaryotic, prokaryotic, cell aggregates, etc.) for the creation of 2-dimnsional or layered 3-dimension arrays of cells and supporting polymeric material. These printed arrays can be used for study of cell interaction, for t...
Published: 1/8/2015   |   Inventor(s): Thomas Boland, Tao Xu, William Wilson
Keywords(s):  
Category(s): Biomedical Sciences
Ying Mei
Dr. Ying Mei is an Assistant Professor in the Department of Bioengineering at Clemson University. He earned his Ph.D. in Material Chemistry from Polytechnic Institute of New York University. Prior to joining Clemson University, Dr. Mei was a guest researcher at the National Institute of Standards and Technology and was a postdoctoral researcher in ...
Jiro Nagatomi
Dr. Jiro Nagatomi is an Associate Professor of Bioengineering at Clemson University. He earned his Ph.D. in Biomedical Engineering from Rensselaer Polytechnic Institute. Prior to joining Clemson, Dr. Nagatomi completed his Postdoctorate in Bioengineering at the University of Pittsburgh. His research interests focus on Mechanobiology, Biomechanics, ...
Jeremy Mercuri
Dr. Jeremy Mercuri is an Assistant Professor of Bioengineering at Clemson University. Prior to joining Clemson, he was a senior research engineer at Stryker and a research engineer at Medtronic Spinal & Biologics. Among his accomplishments, Dr. Mercuri holds two issued patents and several applications. He founded the Laboratory of Orthopaedic T...
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