Search Results - bioprocessing/biotechnology

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Capillary-Channeled Polymer Fibers for Isolating Exosomes
This capillary-channeled polymer (C-CP) fiber technology is a cost efficient and highly selective method to isolate exosomes facilitating widespread use of these cellular fragments for biomarker research, medical diagnostics, and targeted delivery of therapeutics. Exosomes are lipid membrane-derived vesicles secreted by most types of cells, which h...
Published: 7/1/2019   |   Inventor(s): Richard Kenneth Marcus, Terri Bruce, Lei Wang, Sisi Huang, Tyler Slonecki, Rhonda Powell
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Drugs/Pharma - Drug Delivery
Category(s): Advanced Materials, Biomedical Sciences
Multi-Needle Roller for Cell Seeding
Seeding cells within scaffolds or tissues hold great potential for regenerative medicine projects. Until now, cells have been either placed on top of scaffolds, creating multiple layers of superficial cells, or injected manually with a syringe inside the tissues, generating large boluses of cells. None of these approaches generated the homogenous, ...
Published: 1/7/2019   |   Inventor(s): Dan Simionescu, Benjamin Fisher, Harrison Smallwood
Keywords(s): Bioprocessing/Biotechnology, Medical Device, Regenerative Medicine, Tissue Engineering
Category(s): Biomedical Sciences
Electron Donors for Environmental Remediation using Rendered Animal Co-Products
Rendered animal co-products can be used as electron donors to stimulate microbial respiration of reducible environmental contaminants including the chlorinated solvent trichloroethylene (TCE) and the metal hexavalent chromium. This strategy allows for inexpensive treatment, and increased contaminant transformation rates. More than 100 million peop...
Published: 8/10/2018   |   Inventor(s): Kevin Finneran
Keywords(s): Agriculture, Bioprocessing/Biotechnology, Energy - Petrochemical, Environmental/Water Remediation, Petroleum Refining
Category(s): Sustainable Environment
Improved Chemical Functionality of Nylon C-CP Fibers via Microwave Energy (2016-042)
These modified nylon-6 capillary-channeled polymer (C-CP) fibers exhibit greater chemical versatility and higher binding capacity without compromising the physical structure that provides very high throughput and yield in analytical protein separations and downstream processing in comparison to conventional phases. This modification uses microwave...
Published: 8/16/2016   |   Inventor(s): Richard Kenneth Marcus, Liuwei Jiang
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Drugs/Pharma - HIV/Cancer/Other, Textiles/Fibers - Non-Optical/Medical/Other
Category(s): Advanced Materials
Functionalized Lipid Modification of Polymer Surfaces to Affect Chemical Reactivity/Selectivity
This technology from Clemson University utilizes polymer fibers modified with lipids for use in high performance liquid chromatography (HPLC). Polymers have been used as stationary phases for some time, as their small pore sizes allow for better separation of particles. The key factor of this invention is in the modification of the fiber surfaces...
Published: 9/23/2013   |   Inventor(s): Kenneth Christensen, Richard Kenneth Marcus
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Polymers/Composites, Textiles/Fibers - Non-Optical/Medical/Other
Category(s): Biotechnology
Fiber Bundle Cartridges as Chemical Separation Media
Monolithic cartridges including a plurality of nominally aligned polymer fibers can be used as stationary phase materials for liquid chromatography separations. Bundles of fibers are packed together so as to form capillary channels between the fibers. Different polymer compositions permit the “chemical tuning” of the separation process....
Published: 4/23/2012   |   Inventor(s): Richard Kenneth Marcus, Rayman Stanelle, Igor Luzinov, Philip Brown, Yonnie Wu
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Analytical/Instrumentation/Sensors-Non-Medical/NonBiological, Bioprocessing/Biotechnology, Textiles/Fibers - Non-Optical/Medical/Other
Category(s): Advanced Materials
MicroCED: Microbiological-based Chlorinated Ethene Destruction
MicroCED is an innovative treatment technology for the containment, detoxification and elimination of chlorinated ethenes (CE) in the environment. MicroCED consists of several novel microorganisms that are new to science. MicroCED rapidly and completely converts CE to non-toxic, safe end products without production or accumulation of toxic by-produ...
Published: 12/11/2009   |   Inventor(s): David Freedman, William Bratt, Christopher Bagwell, Robin Brigmon, Elizabeth Wood
Keywords(s): Bioprocessing/Biotechnology, Energy - Green Technology, Environmental/Water Remediation, Geology
Category(s): Biotechnology
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