Functionalized Lipid Modification of Polymer Surfaces to Affect Chemical Reactivity/Selectivity

Market Overview:

This technology from Clemson University utilizes polymer fibers modified with lipids for use in high performance liquid chromatography (HPLC).  Polymers have been used as stationary phases for some time, as their small pore sizes allow for better separation of particles.  The key factor of this invention is in the modification of the fiber surfaces.  Due to the polymer’s high level of hydrophobicity, the hydrophobic tails of lipids can adsorb to its surface very easily, leaving the phosphate head to bind with unwanted particles.  Since many types of phosphate heads exist, users can remove very specific types of particles with a simple fiber modification technique. 

Applications:

· High performance liquid chromatography

· Selective bioassays

Benefits:

· Chemical robustness

· Ease of chemical derivatization

· Improved mass transfer due to nonporous nature of the solid

· Convection diffusion throughout the column structure

 

Inventors:                        Kenneth Christensen, Kenneth Marcus

Protection Status:          Patent application filed

Licensing Status:           Available for licensing

CURF Ref No:               2012-094

 

Click here for a full color copy with figures

Patent Information:
Category(s):
Biotechnology
For Information, Contact:
Chris Gesswein
Director of Licensing
Clemson University Research Foundation
agesswe@clemson.edu
Inventors:
Kenneth Christensen
Richard kenneth Marcus
Keywords:
Analytical/Diagnostics/Instru./Sensors-Medical/Biological
Bioprocessing/Biotechnology
Polymers/Composites
Textiles/Fibers - Non-Optical
© 2018. All Rights Reserved. Powered by Inteum