Search Results - Biomedical Sciences

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CrossFit Knee
According to the American Academy of Orthopaedic Surgeons, over 600,000 total knee replacement (TKR) surgeries are performed in the United States each year[1]. The 2015 worldwide TKR market is estimated at $11.7 billion with an average cost of $14,000 per implant[2]. While TKR is the definitive surgical intervention to restore knee function in most...
Published: Apr 20, 2015   |   Inventor(s): Michael Stokes, Luke Pietrykowski, John DesJardins, Roy Rusly
Keywords(s):  
Category(s): Biomedical Sciences
Conventus - A Novel Orthopaedic Drill Guide Docking System
The American Orthopaedic Society for Sports Medicine estimates 5 million arthroscopic surgeries worldwide each year. In the United States, the number of arthroscopic procedures performed between 1999 and 2009 increased 18 fold1. Arthroscopic procedures continue to increase in the US and globally. The US arthroscopic equipment market accounts for 53...
Published: Apr 20, 2015   |   Inventor(s): Michael Stokes, George Seignious, Alan Marionneaux, Allison Santillo, Jeremy Mercuri, Steven Singleton, Brian Keim
Keywords(s): Medical Device
Category(s): Biomedical Sciences
Self-Regenerating Antioxidant Catalysts for Protection of Artificial Implants against Foreign Body Reaction
On an annual basis, medical device companies generate over $200 billion in revenue globally. In the U.S. alone, these companies generated over $85 billion a year in revenues. A large portion of this revenue is derived from sales of devices that are implanted in the human body.1 There is growing demand for advanced coatings to control the interactio...
Published: Apr 20, 2015   |   Inventor(s): Andrew Tennyson, Yamin Htet, Anshuman Mangalum
Keywords(s):  
Category(s): Biomedical Sciences
3D Printed Variable Hardness Foot Orthotics
In 2012, 29.1 million Americans, or 9.3% of the population, had diabetes[1]. At any given moment, between 4-10% of diabetics have a diabetic foot ulcer. Over a lifetime of diabetes, more than 25% of diabetic patients will have a diabetic foot ulcer. In 3-5% of cases, the ulcer will become serious enough that an amputation is required to save a lim...
Published: Apr 20, 2015   |   Inventor(s): John DesJardins, Scott Stanley, Timothy Pruett, Breanne Przestrzelski, Steven Hoeffner, Brian Kaluf, Nuvi Njinimbam, Walter Ballard, Ryan Fitzgerald, Jamee Hooks
Keywords(s):  
Category(s): Biomedical Sciences
Arthroscopic Surgical Graft Delivery System for Shoulder Repair Procedures
According to the American Academy of Orthopaedic Surgeons, approximately 200,000 people in the United Sates require surgery to repair rotator cuff injuries with failure rates for severe tears occurring in 20-70% of these procedures[1]. The high failure rates increases healthcare costs associated with follow-on procedures and extended patient recove...
Published: Apr 20, 2015   |   Inventor(s): Charles Laughlin, Taylor Pate, Nicholas Marais, John Gedney, Richard Hawkins, Greg Colbath
Keywords(s):  
Category(s): Biomedical Sciences
Electrically conductive nanomaterials reinforced cardiac microtissues
According to the World Health Organization (WHO) cardiovascular disease is the leading cause of death worldwide. The mechanism of the disease stems from irreversible death of cardiomyocytes resulting in loss of heart function. Regenerative medicine strategies are emerging to replace the impaired cardiac tissue with functional tissues that can remod...
Published: Apr 20, 2015   |   Inventor(s): Ying Mei, Yu Tan, Dylan Richards, Donald Menick, Bozhi Tan
Keywords(s):  
Category(s): Biomedical Sciences
Multi-functional Nanotherapeutics for Drug Resistant Cancer Treatment (merged w/ 2014-027)
The American Cancer Society projects 589,430 cancer deaths this year in the United States1. Incidence rates of cancer in the United States are expected to reach a rate of 1 in 3 people. Cancer treatment has advanced significantly, however, many chemotherapeutic and radiotherapeutic treatments lack effectiveness due to multidrug resistance (MDR) in ...
Published: Apr 17, 2015   |   Inventor(s): Jeoung Lee
Keywords(s):  
Category(s): Biomedical Sciences
Protein Jet Printing onto Solid Substrata`
Ink-Jet Printing of Viable Cells This patented technology describes the utilization of ink-jet printing of living cells (eukaryotic, prokaryotic, cell aggregates, etc.) for the creation of 2-dimnsional or layered 3-dimension arrays of cells and supporting polymeric material. These printed arrays can be used for study of cell interaction, for t...
Published: Jan 8, 2015   |   Inventor(s): Thomas Boland, Tao Xu, William Wilson
Keywords(s):  
Category(s): Biomedical Sciences
Nano EDL Capacitor Based Biosensors
This technology features the development and application of a nanoscale electrical double layer (EDL) capacitor based biosensor. It takes advantage of the fact that the capacitance of an EDL device varies very sensitively with the charge and dielectric conditions of the nearby space spanning from the electrode surface to a few nanometers out to dev...
Published: Aug 19, 2014   |   Inventor(s): Guigen Zhang
Keywords(s): Analytical Tools / Instrumentation, Diagnostics / Sensors, Bioinstrumentation
Category(s): Biomedical Sciences
Easy Incorporation of PEGylated Lysines and Glutamines in Peptides
With peptide drugs such as Victoza reaching blockbuster status, the rapid proteolysis and clearance of peptides from the body is becoming an increasing concern. The PEGylation strategies used with protein drugs simply don’t work and PEG polymers are too large for peptides. Peptides are easy to synthesize using solid phase peptide synthesis...
Published: Jun 30, 2014   |   Inventor(s): Modi Wetzler, Paris Hamilton
Keywords(s):  
Category(s): Biomedical Sciences
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