Search Results - Biomedical Sciences

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Multi-functional Nanotherapeutics for Targeted Drug and Gene Therapy
Novel Polymeric Micelle Nanoparticle Enables Targeted Drug and Nucleic Acids DeliveryMarket OverviewThis multi-functional polymeric micelle nanocarriers serve as a platform technology for combinatorial delivery of multiple bioactive molecules for the treatment of pathological diseases or repair of injured tissues. With a growing population of cance...
Published: 6/22/2016   |   Inventor(s): Jeoung Lee
Category(s): Biotechnology, Biomedical Sciences
3D Printed Variable Hardness Foot Orthotics with Patient-Specific Fit
Low-cost, Patient-specific Foot Orthotics Evolves to Meet Patient Needs over TimeMarket OverviewThis custom-fit foot orthotic uses 3D printing, providing a clinician-to-patient manufacturing cycle that produces custom-fit foot orthotics in reduced time and lower costs. Over 29 million Americans, or 9.3 percent of the population, have diabetes. At a...
Published: 6/20/2016   |   Inventor(s): John DesJardins, Scott Stanley, Breanne Przestrzelski, Brian Kaluf, Timothy Pruett, Steven Hoeffner
Category(s): Biomedical Sciences
PEGylated Amino Acids for Easier Peptide Synthesis
Pre-PEGylated Amino Acids Resulting in Peptides with Increased Solubility Easier ProductionMarket OverviewThese pre-PEGylated (Poly Ethylene Glycol) amino acids can be used directly in solid phase peptide synthesis (SPPS) with no need for orthogonal protection schemes, making the creation of PEGylated peptides easier for manufacturers. This approac...
Published: 6/10/2016   |   Inventor(s): Modi Wetzler, Paris Hamilton
Category(s): Biomedical Sciences
Coventus: Double Drill Guide for Use in Arthroscopic Orthopedic Surgery
Reduces Surgical Time and Provides Increased Efficiency in Arthroscopic ProceduresMarket OverviewConventus is an orthopedic drill guide accessory that allows surgeons to quickly attach and secure two bone tunnel drill guides to one unit. The American Orthopedic Society for Sports Medicine estimates five million arthroscopic surgeries take place wor...
Published: 6/3/2016   |   Inventor(s): Michael Stokes, George Seignious, Alan Marionneaux, Allison Santillo, Jeremy Mercuri, Adam Marrocco, Nicholas Freeman
Keywords(s): Medical Device
Category(s): Biomedical Sciences
Bioprosthetic Heart Valves that Resist Structural Degradation and Stiffening
Crosslinking Chemistry Increases Durability and Endurance of Bioprosthetic Heart Valve ReplacementsMarket OverviewThis treatment stabilizes the connective tissue present in bioprosthetic heart valves to create durable and long-lasting replacement heart valves. There are approximately 300,000 heart valve transplantations performed globally each year...
Published: 6/3/2016   |   Inventor(s): Narendra Vyavahare, Hobey Tam
Keywords(s): Cardiovascular Biomaterials, Molecular Therapies
Category(s): Biomedical Sciences
Locking Total Knee Replacement Design for Treating Knee Extensor Weakness
“Lock-key,” Patient Controlled Mechanism for Knee Replacement that Allows Ambulation Market OverviewThis design allows patients to selectively lock the knee in full extension for the purposes of ambulation and unlock free rotation when desired. According to the American Academy of Orthopedic Surgeons, over 600,000 total knee replacement...
Published: 6/3/2016   |   Inventor(s): Eric Lucas, John DesJardins, Kim Chillag, Frank Voss
Keywords(s): Medical Device, Orthopedic, Biomaterials Implant Design, Orthopaedic Mechanics
Category(s): Biomedical Sciences
Radio-Opaque Biodegradable Polymers for Deep Tissue Imaging using X-ray
X-ray Imaging for Non-Invasive Monitoring of Polymer Degradation and IntegrityMarket OverviewThese biodegradable polymers composed of FDA approved materials can be used to non-invasively image polymeric implants, coatings, and nanoparticles to measure degradation and defects, thereby preventing possible implant failure and increasing patient health...
Published: 5/26/2016   |   Inventor(s): Brooke Van Horne, Frank Alexis, Daniel Whitehead
Category(s): Biomedical Sciences
Biologic Hydrogel Material for Combatting Intervertebral Disc Degeneration
Provides Early-Stage Intervention for Intervertebral Disc Degeneration via a Biomimetic Nucleus Pulposus ScaffoldMarket OverviewThis hydrogel scaffold can be used as an early-stage intervention for combatting intervertebral disc (IVD) degeneration (IDD). Lower back pain is a significant burden that affects nearly 85 percent of all people, 40 percen...
Published: 5/25/2016   |   Inventor(s): Christopher Fernandez, Jeremy Mercuri
Category(s): Biomedical Sciences
Collagen Patch to Repair Intervertebral Disc Herniation and Degeneration
Helps Restore IVD Function and Alleviate Pain in Patients, Minimizing Healthcare Expenditures Associated with Re-operation and Spinal Fusion SurgeriesMarket OverviewThis collagen-based patch is a multi-laminate, ply-angle-ply sheet-based reinforcement used to biologically augment and facilitate repair of the annulus fibrosus (AF) of the interverteb...
Published: 5/24/2016   |   Inventor(s): Rachel McGuire, Ryan Borem, Jeremy Mercuri
Category(s): Advanced Materials, Biomedical Sciences, Biotechnology
Shape-Memory Sponge Hydrogel for Tissue Engineering Applications
Resilient and Hydrophilic Biomaterial with Shape-Memory Sponge Characteristics for Tissue Replacement Market OverviewThis hydrogel composite is composed of elastin, glycosaminoglycan and collagen (EGC) that exhibits unique shape-memory sponge characteristics . This EGC hydrogel has broad applications in tissue engineering and biomaterials, specifi...
Published: 5/18/2016   |   Inventor(s): Dan Simionescu, Jeremy Mercuri
Keywords(s): Biomaterials, Medical Device, Regenerative Medicine, Stem-Cell Engineering, Tissue Engineering
Category(s): Biomedical Sciences
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