Search Results - Biomedical Sciences

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Cell Plate Insert for Biomaterials Evaluation
Understanding the effect of intimate contact between a material and a mammalian cell or bacteria is important for applications such as cytotoxicity evaluations for medical device materials, tissue engineering scaffolds for tissue and organ regeneration, and testing the anti-microbial activity of packaging materials. Existing approaches to evaluate...
Published: Jul 22, 2014   |   Inventor(s): Matthew Gevaert, Karen Burg
Keywords(s): Biomaterials Implant Design, Tissue Engineering
Category(s): Biomedical Sciences
Targeted Drug Delivery System for Enhancing Cancer Drug Efficacy
This technology relates to compositions and methods for drug delivery systems to target difficult-to-treat cancers, specifically glioblastoma, brain cancer. Functionalized nanoparticles (NPs) can be made to target specific cancer cells and improve uptake of therapeutic agents thereby increasing efficacy and reducing systemic side effects. Challeng...
Published: Jul 1, 2014   |   Inventor(s): Frank Alexis, Bruce Frankel
Keywords(s):  
Category(s): Biomedical Sciences
Easy Incorporation of PEGylated Lysines and Glutamines in Peptides
With peptide drugs such as Victoza reaching blockbuster status, the rapid proteolysis and clearance of peptides from the body is becoming an increasing concern. The PEGylation strategies used with protein drugs simply don’t work and PEG polymers are too large for peptides. Peptides are easy to synthesize using solid phase peptide synthesis...
Published: Jun 30, 2014   |   Inventor(s): Modi Wetzler, Paris Hamilton
Keywords(s):  
Category(s): Biomedical Sciences
Cellular Separation Device for Tissue Engineering and Diagnostic Applications
Cancer is the second leading cause of death in the US and has impacted most Americans in some way. The current diagnostic tests are unreliable and fail to capture the complexity and heterogeneity of a cancer biopsy. In fact, 1 in 4 cancer cases will have delayed diagnosis or misdiagnosis. This alarming statistic supports the need for more reliable...
Published: Jun 6, 2014   |   Inventor(s): Karen Burg, Suzanne Tabbaa
Keywords(s):  
Category(s): Biomedical Sciences
Biodegradable X-Ray Imaging Polymers
The global biomaterials market is projected to swell to almost $90 billion by 2017. The polymeric segment of this market is growing at perhaps the fastest rate, with a compound annual growth rate of 22.1%1. Synthetic polymeric biomaterials can be designed to possess properties that make them advantageous for use as staples, screws, stents, and ot...
Published: Apr 23, 2014   |   Inventor(s): Brooke Van Horne, Frank Alexis
Keywords(s):  
Category(s): Biomedical Sciences
Advanced Electromagnetic Catheter Tracking System for Fluoroscopy and Three-dimensional Echocardiography
Inventors from Clemson University and Medical University of South Carolina have developed new systems and methods for image-guided surgery. To facilitate guidance of the instrument during the surgery, the estimated position of an instrument relative to the plurality of projection images can be displayed. The position of the instrument can be tracke...
Published: Jan 27, 2014   |   Inventor(s): David Kwartowitz, Hamilton Baker
Keywords(s): Image-Guided Surgery, Bioinstrumentation, Cardiovascular, Medical Device
Category(s): Biomedical Sciences
Duck, Duck, Punch: A Post-stroke Neurorehabilitation Game
Strokes are the second leading cause of permanent disability worldwide [1]. Upper extremity (UE) motor impairment occurs in 85% of survivors, which causes difficulty in every-day reaching and grabbing tasks such as brushing teeth or picking up a fork. UE impairment therapy is currently based on repetitive practice of reaching and grasping tasks, wh...
Published: Dec 9, 2013   |   Inventor(s): Patrick Dukes, Austen Hayes, Larry Hodges, Michelle Woodbury
Keywords(s):  
Category(s): Biomedical Sciences
The Velox - A Mandibulomaxillary Fixation Device
Almost 1 million mandible and/or maxilla fracture repair surgeries are performed in the United States each year. The procedure corrects the alignment of bones that have fractured either after major trauma, tumor removal, or deep facial tissue repair. To stabilize and maintain proper anatomic positioning the patient is most commonly fitted with an E...
Published: Oct 17, 2013   |   Inventor(s): Tyler Youngman, Natalie Patzin, John O'Donnell, Jeff Willis, Robert Brown
Keywords(s): Medical Device, Bioengineering Senior Design, Orthopaedic Mechanics
Category(s): Biomedical Sciences
Novel Expanding Cannula for Arthroscopic Shoulder Surgery
In recent years, a large emphasis has been placed on the advancement of minimally invasive surgical procedures, especially arthroscopic surgeries. In the US, approximately 60,000 arthroscopic shoulder surgeries are performed annually [1]. Many of these procedures require the use of one or more cannulae: these are tubes that provide a space for s...
Published: Oct 8, 2013   |   Inventor(s): Kayla Perry, William Sumner, Samuel Pollard, Casey Kukielski, Olin Mefford, Richard Hawkins
Keywords(s): Bioengineering Senior Design, Orthopaedic Mechanics
Category(s): Biomedical Sciences
Fit Prosthetics: IDEAL Socket
Currently, there are around 1.7 million amputees in the United States of which approximately 900,000 are lower limb amputees [1]. The number of amputees in the US is steadily increasing every year due to peripheral vascular disease and diabetes related amputations, which account for 82% of all amputations [1]. The prosthetics market in the United S...
Published: Oct 8, 2013   |   Inventor(s): Joshua Williams, Samuel Karns, Ryan Freed, Molly Russell, Brian Kaluf
Keywords(s): Biomaterials Implant Design, Bioengineering Senior Design, Orthopaedic Mechanics
Category(s): Biomedical Sciences
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