Search Results - Biomedical Sciences

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New Material for Transcatheter Bioprosthetic Heart Valves
This technology features a biomaterial useful for bioprostheses, such as bioprosthetic heart valves (BHVs), in which the fixed tissue has improved elastic properties. The high elastin-containing biomaterial is further characterized by having anisotropic properties wherein the biological material has a greater stiffness in one direction and a greate...
Published: 11/14/2018   |   Inventor(s): Narendra Vyavahare, Dan Simionescu
Keywords(s): Biomaterials - Cardiovascular, Medical Device
Category(s): Biomedical Sciences
Multilayerd Osteochondral Implant for Enhanced Bone Healing
This novel off-the-shelf osteochondral implant exhibits a highly similar microarchitecture to that of native bone and cartilage, allowing better integration and mechanical support to the damaged tissue after implantation. Approximately 2,000,000 surgical procedures were performed to repair chondral defects in the United States between 2004-2011, wi...
Published: 9/19/2018   |   Inventor(s): Alan Marionneaux, Jeremy Mercuri, Joshua Walters
Keywords(s): Biomaterials - Orthopaedic, Orthopaedics-Biologics/Tissue Engr/Regen Medicine, Regenerative Medicine
Category(s): Biomedical Sciences
Smart Orthopedic Screws for Imaging through Tissue (2012-018)
These smart orthopedic screws allow physicians to noninvasively detect and monitor the health of bone implants, potentially preventing infection and implant loosening over time. In the United States, musculoskeletal injuries affect over 28 million patients annually – at least two million of which require fracture fixation surgery. These surge...
Published: 8/21/2018   |   Inventor(s): Jeffrey Anker, Jonathan Heath, Dakota Anderson, Melissa Rogalski
Keywords(s): Bioinstrumentation, Biomaterials - Orthopaedic, Medical Device, Orthopaedics - Orthotics/Prosthetics/Hardware/Other
Category(s): Biomedical Sciences
Durable Polymeric Antimicrobial Coating for Orthopedics (2017-059)
External fixation is a well-established orthopedic practice in which fractured bones or fusion sites are immobilized for healing by placing wires and/or pins into the bone on either side. Unfortunately, both superficial and deep tissue infections are prevalent with the use of external fixators, particularly Staphylococcal infections. The economic b...
Published: 2/8/2018   |   Inventor(s): Alexey Vertegel, Igor Luzinov, Christopher Gross, Dmitry Gil, Nikolay Borodinov
Keywords(s): Biomaterials - Orthopaedic, Coatings, Medical Device, Orthopaedics - Orthotics/Prosthetics/Hardware/Other
Category(s): Biomedical Sciences
Enhanced Color Sensitivity for Colorimetric-based Chemical Analysis (2017-055)
This novel technology for colorimetric chemical analysis significantly enhances color change intensity and uniformity upon exposure to a target substance when compared to conventional color-indicating substrates. This technology thus has application to any colorimetric-based chemical assay, such as urinalysis. The global urinalysis market was estim...
Published: 1/16/2018   |   Inventor(s): Robert Latour, George Chumanov, Alexandra Cholewczynski
Category(s): Biomedical Sciences, Biotechnology
Site-specific Therapy for Diseases Affecting Connective Tissues (2017-028)
Cardiovascular diseases, including atherosclerosis and other coronary illnesses, are the leading cause of death globally. Current treatments for these conditions such as stents and other surgical procedures present risks of arterial damage, strokes, and potential infections. Additionally, some individuals are altogether ineligible for surgical proc...
Published: 11/6/2017   |   Inventor(s): Narendra Vyavahare, Charles Rice, Nasim Nosoudi, Saketh Karamched, Vaideesh Parasaram
Category(s): Biomedical Sciences
Nano EDL Capacitor Based Biosensors
This technology features the development and application of a nanoscale electrical double layer (EDL) capacitor based biosensor. It takes advantage of the fact that the capacitance of an EDL device varies very sensitively with the charge and dielectric conditions of the nearby space spanning from the electrode surface to a few nanometers out to dev...
Published: 8/4/2017   |   Inventor(s): Guigen Zhang
Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioinstrumentation
Category(s): Biomedical Sciences
Biphasic Osteochondral Construct for Cartilage Tissue Repair (09-026)
This osteochondral construct is seeded with mesenchymal stem cells to encourage repair of cartilage and subchondral bone in synovial joints. The global market for tissue engineering and regeneration is expected to grow from $13.6 billion in 2016 to $60.8 billion in 2021, in part due to the 5.4 million patients projected to require joint and cartila...
Published: 3/9/2017   |   Inventor(s): Karen Burg, Scott Maxson
Keywords(s): Biomaterials - Orthopaedic, Medical Device, Orthopaedics-Biologics/Tissue Engr/Regen Medicine, Tissue Engineering
Category(s): Biomedical Sciences
Protein Nano-Object Software for Biomolecular Modeling (2013-020)
This Protein Nano-Object Integrator (ProNOI) software allows for researchers to generate atomic-style geometrical objects in the desired shape and dimensions either from cry-electron photography or user-specified shape. Biomolecular modeling is important to address biological problems at the molecular level and to understand the interactions betwee...
Published: 3/1/2017   |   Inventor(s): Emil Alexov, Nicholas Smith
Category(s): Biomedical Sciences, Biotechnology
Software Platform that Enables Large Scale Brain Wave Data Collaboration (2014-081)
This software platform, EEGnet, provides researchers with an efficient database to view and interact with electroencephalography (EEG) brain wave data. EEG is an electrophysical monitoring system that records electrical activity in the brain and is used most often to diagnose epilepsy. Traditionally, EEG research has been limited due to a lack of l...
Published: 1/23/2017   |   Inventor(s): Brian Dean, Jonathan Halford
Category(s): Biotechnology, Biomedical Sciences
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