Search Results - Biomedical Sciences

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Biphasic Osteochondral Construct for Cartilage Tissue Repair (09-026)
This osteochondral construct is seeded with mesenchymal stem cells to encourage repair of cartilage and subchondral bone in synovial joints. The global market for tissue engineering and regeneration is expected to grow from $13.6 billion in 2016 to $60.8 billion in 2021, in part due to the 5.4 million patients projected to require joint and cartila...
Published: 3/9/2017   |   Inventor(s): Karen Burg, Scott Maxson
Keywords(s): Biomaterials, Fibers & Films, Medical Device, Biomaterials Implant Design, Orthopaedic Mechanics, Tissue Engineering
Category(s): Biomedical Sciences
Protein Nano-Object Software for Biomolecular Modeling (2013-020)
This Protein Nano-Object Integrator (ProNOI) software allows for researchers to generate atomic-style geometrical objects in the desired shape and dimensions either from cry-electron photography or user-specified shape. Biomolecular modeling is important to address biological problems at the molecular level and to understand the interactions betwee...
Published: 3/1/2017   |   Inventor(s): Emil Alexov, Nicholas Smith
Category(s): Biomedical Sciences, Biotechnology
Dual Peptide Targeted Delivery System for Oral Cancer Therapeutics (2015-049)
This dual peptide co-delivers small interfering RNAs (siRNAs) into cancer cells overexpressing the epidermal growth factor receptor (EGFR), enabling efficient gene silencing and improving oral cancer therapeutics. According to World Health Organization, approximately 450,000 new cases of oral cancer are found worldwide each year. RNA interference i...
Published: 1/23/2017   |   Inventor(s): Angela Alexander-Bryant, Andrew Jakymiw
Category(s): Biomedical Sciences, Biotechnology
Software Platform that Enables Large Scale Brain Wave Data Collaboration (2014-081)
This software platform, EEGnet, provides researchers with an efficient database to view and interact with electroencephalography (EEG) brain wave data. EEG is an electrophysical monitoring system that records electrical activity in the brain and is used most often to diagnose epilepsy. Traditionally, EEG research has been limited due to a lack of l...
Published: 1/23/2017   |   Inventor(s): Brian Dean, Jonathan Halford
Category(s): Biotechnology, Biomedical Sciences
Electromagnetic Catheter Tracking System to Reduce Radiation Exposure (2011-122)
This electromagnetic catheter tracking system improves surgical intervention while reducing radiation exposure to pediatric cardiology patients. As congenital heart disease (CHD) cases continue to rise in children, the pediatric interventional cardiology market is expected rise as well, reaching a value of $1,379.1 million by 2018. While many thera...
Published: 1/20/2017   |   Inventor(s): David Kwartowitz, Hamilton Baker, Fuad Mefleh
Keywords(s): Image-Guided Surgery, Bioinstrumentation, Cardiovascular, Medical Device
Category(s): Biomedical Sciences
Portable Device for Diagnosis and Monitoring of Rotator Cuff Disease (2012-106)
This device utilizes ultrasound imaging to diagnose and monitor rotator cuff injuries. Each year there are over three million new cases of rotator cuff disease. Among those affected, more than half the population over 60 suffer from rotator cuff disease. Shoulder injuries, and particularly rotator cuff disease, can be difficult to diagnose. To give...
Published: 1/20/2017   |   Inventor(s): David Kwartowitz, Erika Trent, Fuad Mefleh, Vipul Raikar, Delphine Dean
Keywords(s): Medical Device, Bioinstrumentation, Orthopaedic Mechanics
Category(s): Biomedical Sciences
Rib Fixation Device for Treatment of Early Onset Scoliosis and Spinal Deformities (2016-007)
This rib fixation device attaches expanded titanium hooks on two or four ribs, improving stability of fixation for safer management of upper thoracic instabilities. With early onset scoliosis (EOS) having an incidence of approximately 1-2 per 1000 births, and with frequent complications of originally untreated individuals, care for severe thoracic ...
Published: 1/20/2017   |   Inventor(s): Hai Yao, Gregory Wright, Richard Gross
Category(s): Biomedical Sciences
Biocompatible Hydrogel for Enhanced Hydrophobic Drug Delivery (04-032)
This hydrogel is tailored during fabrication to release hydrophobic drugs at varying molecular weights to decrease treatment intervals of chronic disorders. The drug delivery market was valued at $1,048.1 billion globally in 2015 and is expected to grow to $1,504.7 billion by 2020, driven by needs for ease of use, proper dosage delivery, and superi...
Published: 1/17/2017   |   Inventor(s): Andrew Metters, Srinivas Chollangi
Keywords(s): Biomaterials, Drugs / Pharma
Category(s): Biomedical Sciences
High Resolution Analyte Recovery with Improved Selectivity (2014-083)
This purification system utilizes multiple process streams and chromatographic techniques to concentrate and recover high value analytes. The process permits scalability from analytical to preparative liquid chromatography in a modular format that can be used to minimize overall cost to the consumer without loss of selectivity. Currently used proce...
Published: 11/2/2016   |   Inventor(s): Feng Chen, Gregory Jones
Category(s): Biotechnology, Biomedical Sciences
Bi-Functional RGD Peptide to Promote Therapeutic Angiogenesis, Treat Ischemic Diseases (2016-060)
This bi-functional RGD peptide helps identify ligands and improve functions of endothelial cells, allowing for the development of biomaterials to treat ischemic diseases. According to the Center for Disease Control and Prevention, over 795,000 people in the United States suffer a stroke each year. Of these cases, 87 percent are caused by ischemia &...
Published: 10/11/2016   |   Inventor(s): Ying Mei, Jia Jia, Chung-Jen Chou
Keywords(s): Biomedical Engineering, Biomaterials, Medical Device
Category(s): Biomedical Sciences
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