Search Results - drugs%2fpharma+-+drug+delivery

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Myocardial In Vitro Platform for Drug Development and Cardiotoxicity Screening

This myocardial in vitro screening platform provides relevant physiological stimuli enabling analysis of output metrics with direct clinical relevance to cardiac function. While drug discovery is robust and well-funded, a very low percentage of experimental drug candidates reach the marketplace as FDA-approved therapies. This translates into billions...

Published: 10/8/2024 | Inventor(s): William Richardson, Samuel Coeyman, Jonathan Heywood

Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Biomaterials - Cardiovascular, Cardiovascular, Diabetes, Drugs/Pharma - Antibiotics, Drugs/Pharma - Drug Delivery, Drugs/Pharma - HIV/Cancer/Other, Medical Device, Molecular Therapies, Oncology/Cancer, Regenerative Medicine, Tissue Engineering

Category(s): Biomedical Sciences

Capillary-Channeled Polymer Fibers for Isolating Exosomes

This capillary-channeled polymer (C-CP) fiber technology is a cost efficient and highly selective method to isolate exosomes facilitating widespread use of these cellular fragments for biomarker research, medical diagnostics, and targeted delivery of therapeutics. Exosomes are lipid membrane-derived vesicles secreted by most types of cells, which hold...

Published: 10/8/2024 | Inventor(s): Richard Marcus, Terri Bruce, Lei Wang, Sisi Huang, Tyler Slonecki, Rhonda Powell

Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Drugs/Pharma - Drug Delivery

Category(s): Advanced Materials, Biomedical Sciences

Injectable Joint Lubricant for Treating Osteoarthritis

This dextran-based hydrogel uses phospholipid delivery to treat degenerative joint diseases, also known as osteoarthritis. Osteoarthritis is the most common type of arthritis, affecting over 27 million Americans over the age of 25. It becomes more common with age, often affecting the neck, lower back, knees, and hips. Normally synovial fluid, a natural...

Published: 10/8/2024 | Inventor(s): Julie-Ann Burdick, Martine Laberge, Gary Lickfield

Keywords(s): Biomaterials - Other, Drugs/Pharma - Drug Delivery, Medical Device, Tissue Engineering

Category(s): Biomedical Sciences

Topical Application of Hydrogel for the Treatment of Acute Spinal Cord Injury

This hydrogel can be used for the non-invasive treatment of acute spinal cord injuries by applying topically to the injury site. According to the Centers for Disease Control and Prevention, about 450,000 people in the United States are currently living with a spinal cord injury and 12,000 new cases develop each year. The cost of rehabilitation and on-going...

Published: 10/8/2024 | Inventor(s): Xing Jin, Vibhor Krishna, Xuejun Wen, Ning Zhang

Keywords(s): Biomaterials - Neurology, Drugs/Pharma - Drug Delivery, Molecular Therapies, Regenerative Medicine, Tissue Engineering

Category(s): Biomedical Sciences

Method and Material to Extend the Life of Total Joint Replacements through Wear

More than 500,000 joint replacements occur in the US each year and demand for joint replacements will grow an estimated 175 percent for total hip replacements and six-fold for total knee replacements by 2030 (CDC report “Health United States 2009”). These replacements typically last about 10 years or more, but as the patients live longer...

Published: 10/8/2024 | Inventor(s): John DesJardins, Martine Laberge, Cassandra Wright-Walker

Keywords(s): Biomaterials - Orthopaedic, Drugs/Pharma - Drug Delivery, Medical Device, Orthopaedics - Orthotics/Prosthetics/Hardware/Other

Category(s): Biomedical Sciences