Search Results - bioprocessing%2fbiotechnology

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Capillary-Channeled Polymer Fibers for Isolating Exosomes

This capillary-channeled polymer (C-CP) fiber technology is a cost efficient and highly selective method to isolate exosomes facilitating widespread use of these cellular fragments for biomarker research, medical diagnostics, and targeted delivery of therapeutics. Exosomes are lipid membrane-derived vesicles secreted by most types of cells, which hold...

Published: 10/8/2024 | Inventor(s): Richard Marcus, Terri Bruce, Lei Wang, Sisi Huang, Tyler Slonecki, Rhonda Powell

Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Drugs/Pharma - Drug Delivery

Category(s): Advanced Materials, Biomedical Sciences

Multi-Needle Roller for Cell Seeding

Seeding cells within scaffolds or tissues hold great potential for regenerative medicine projects. Until now, cells have been either placed on top of scaffolds, creating multiple layers of superficial cells, or injected manually with a syringe inside the tissues, generating large boluses of cells. None of these approaches generated the homogenous, high...

Published: 10/8/2024 | Inventor(s): Dan Simionescu, Benjamin Fisher, Harrison Smallwood

Keywords(s): Bioprocessing/Biotechnology, Medical Device, Regenerative Medicine, Tissue Engineering

Category(s): Biomedical Sciences

Electron Donors for Environmental Remediation using Rendered Animal Co-Products

Rendered animal co-products can be used as electron donors to stimulate microbial respiration of reducible environmental contaminants including the chlorinated solvent trichloroethylene (TCE) and the metal hexavalent chromium. This strategy allows for inexpensive treatment, and increased contaminant transformation rates. More than 100 million people...

Published: 10/8/2024 | Inventor(s): Kevin Finneran

Keywords(s): Agriculture, Bioprocessing/Biotechnology, Energy - Petrochemical, Environmental/Water Remediation, Petroleum Refining

Category(s): Sustainable Environment

Functionalized Modification of Polymers for HPLC

These polymer fibers, used as stationary phases in high-performance liquid chromatography (HPLC), enable a high level of selectivity and throughput, thus increasing efficiency. Chromatography is a method used by scientists to separate organic and inorganic compounds for further analysis. Currently, over 60% of chemical analysis worldwide is done in...

Published: 10/8/2024 | Inventor(s): Kenneth Christensen, Richard Marcus

Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Bioprocessing/Biotechnology, Polymers/Composites, Textiles/Fibers - Non-Optical/Medical/Other

Category(s): Biotechnology

Fiber Bundle Cartridges as Chemical Separation Media

Monolithic cartridges including a plurality of nominally aligned polymer fibers can be used as stationary phase materials for liquid chromatography separations. Bundles of fibers are packed together so as to form capillary channels between the fibers. Different polymer compositions permit the “chemical tuning” of the separation process....

Published: 10/8/2024 | Inventor(s): Richard Marcus, Rayman Stanelle, Igor Luzinov, Philip Brown, Yonnie Wu

Keywords(s): Analytical/Diagnostics/Instru./Sensors-Medical/Biological, Analytical/Instrumentation/Sensors-Non-Medical/NonBiological, Bioprocessing/Biotechnology, Textiles/Fibers - Non-Optical/Medical/Other

Category(s): Advanced Materials

MicroCED: Microbiological-based Chlorinated Ethene Destruction

MicroCED is an innovative treatment technology for the containment, detoxification and elimination of chlorinated ethenes (CE) in the environment. MicroCED consists of several novel microorganisms that are new to science. MicroCED rapidly and completely converts CE to non-toxic, safe end products without production or accumulation of toxic by-products....

Published: 10/8/2024 | Inventor(s): David Freedman, William Bratt, Christopher Bagwell, Robin Brigmon, Elizabeth Wood

Keywords(s): Bioprocessing/Biotechnology, Energy - Green Technology, Environmental/Water Remediation, Geology

Category(s): Biotechnology