Using miR319 gene to Enhance Abiotic Stress Tolerance in Transgenic Plants

Market Overview:

This overexpression of the micro RNA (miR319) gene improves salt and drought tolerance in transgenic plants, enhancing crop performance under adverse environmental conditions. Plant micro RNAs are a class of endogenous small noncoding RNAs that play essential roles in diverse biological processes, including plant responses to environmental stresses and various aspects of plant development. By harnessing the potential of these RNA, it’s possible to improve the quality and safety of agricultural products impacted by abiotic stress such as drought and salinity. Clemson University researchers have cloned the rice miR319 gene and evaluated the feasibility of using this gene in turfgrass for improved plant response to abiotic stress. By manipulating mircoRNA 319 gene expression for enhanced abiotic stress resistance, there is great potential for enhancing crop performance under adverse conditions.


Application                                                        Stage of Development

Agriculture production; biotechnology              Ready for field testing



• Demonstrates increased tolerance to drought and salt stress, enhancing crop performance under adverse

  environmental conditions

• Utilizes an efficient method to produce plants that are capable of withstanding adverse environments, improving

  crop productivity with high efficiency


Technical Summary

Data demonstrates that transgenic plants overexpressing miR319 exhibit improved tolerance to drought and salt stress. In studies, transgenic plants overexpressing miR319 exhibited better water retention and cell membrane integrity than controls under salt stress. Additionally, transgenic plants accumulate less sodium than controls under salinity conditions. Overexpression of mi319 improves drought tolerance in transgenic plants that is associated with enhanced water retention and cell integrity and well-maintained photosynthesis.


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Inventors:            Hong Luo, Qian Hu, Man Zhou, Dayong Li


Patent Type:         Provisional; Utility


Serial No:              61/556,852; 13/672,320


CURF Ref:          2011-026


Patent Information:
For Information, Contact:
Chris Gesswein
Director of Licensing
Clemson University Research Foundation
Hong Luo
Dayong Li
Man Zhou
Qian Hu
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