Use of Ribbed Polymer Fibers as Stationary/Support Phases for Chemical Separations by Liquid Chromatography or for Waste Stream Remediation

Market Overview:

This technology features the usage of a novel cross-section of polymer fibers for various applications such as liquid chromatography to separate, quantify, and analyze contents of a chemical mixture.  Bundles of the novel high surface area fibers such as the 4DGTM fibers (see CURF reference 00-024) are packed in columns. Different polymer compositions permit the "chemical tuning" of the separation process.  Use of channeled fibers allows a wide range of liquid flow rates with very low backing pressures.  In addition, the fibers can be physically or chemically derivatized to target specific analytes for separation from a test sample. The fibers are easily packed into a micropipette tip or a conduit for use with a fluid flow device such as an aspirator or a pump. The resultant devices can then be used for isolation and pre-concentration of analytes from samples, for instance for proteins from buffer solutions or extraction of pollutants from remote locations.


· High performance liquid chromatography (HPLC)

· Capillary liquid chromatography (cap-LC)

· Separations of specialty chemicals

· Waste remediation/immobilization

· Purification of liquid streams (process waste, drinking water, pure solvents)

· Selective extraction/immobilization of cell matter


· Overcomes problem of high back pressures needed for densely packed columns

· Customized applications possible

· Adaptable to current technology configurations


Inventors:                        Ken Marcus

Protection Status:          Patent issued # 7,374,673

Licensing Status:           Available for licensing

CURF Ref No:                02-003


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Patent Information:
Advanced Materials
For Information, Contact:
Chris Gesswein
Director of Licensing
Clemson University Research Foundation
Richard Kenneth Marcus
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