Conductive Nanofiber Composite Fabric Biosensor and Method for its Fabrication

Market Overview:

This biosensor provides a means for rapid, sensitive, and specific detection of bacterial strains at the point of care. It is capable of detecting pathogenic bacteria through an impedance method by tracking the phase and magnitude response from a generated sinusoidal signal. Current approaches to infection assessment rely on imaging technologies or swab cultures, which are effective but expensive in time and personnel costs. Additionally, assessment in a clinical setting is subjective and highly based on skill level of the clinician. This creates the need to develop a technology that facilitates improving patient outcomes and limiting medical costs. The global biosensors market is expected to reach $36 million by 2027, growing at a CAGR of 7.9%. In this high demand market environment, Clemson University researchers have created a method to produce nanofiber-based impedance and electrochemical biosensors that can be tuned to specific bacterial species and quantification that can be accomplished to provide information about current state as well as growth rate.

 

Application                                                                   Stage of Development

Biosensor, Wound Healing,                                      Proof of concept

Biotechnology

        

Advantages

  • Has the ability to monitor bacteria growth with a wearable application
  • Can utilize solution blow spinning to incorporate nanoparticles for antimicrobial and antioxidative properties
  • Allows not only for the detection of bacteria, but also any precursors that can predict an infection not mature yet

 

Technical Summary

This technology includes a method to produce nanofiber-based impedance and electrochemical biosensors. It is capable of producing biosensors that can detect pyocyanin from pseudomonas aeruginosa, potassium ferricyanide, and methylene blue. Solution blow spinning of nanofibers is used to develop conductive electrical nanofibers and provide dielectric substrate for the biosensor electrodes. Carbon nanotubes have been used as a conductive filler material to generate conductive nanofiber mats.

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Inventor:                       Jordon Gilmore

Patent Type:                  N/A

Serial Number:             N/A

CURF Ref No:              2020-066

Patent Information:
Category(s):
Biotechnology
For Information, Contact:
Andy Bluvas
Technology Commercialization Officer
Clemson University Research Foundation
bluvasa@clemson.edu
Inventors:
Keywords:
Analytical/Diagnostics/Instru./Sensors-Medical/Biological
Bioinstrumentation
Medical Device
Textiles/Fibers - Non-Optical/Medical/Other
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